The main component of Cialis is Tadalafil which was developed by the well-known pharmaceutical company Glaxo Wellcome. Studies of this drug started in 1991, but during several years  they were unsuccessful. However, in 1993, the biotechnical company ICOS Corporation announced a fairly serious statement regarding the connection of IC351, an inhibitor of the enzyme phosphodiesterase type 5.

At the same time, the research laboratory of the corporation Pfizer was given Sildenafil, which soon became known to the whole world under the name of Viagra. Despite the fact that scientists from both laboratories worked in one direction, Pfizer was somewhat ahead of the competition, presenting its drug. But the company ICOS did not give up, and in 1994, patented its offspring, and then began large-scale clinical trials involving men who had erectile dysfunction.

We can say that the tests were quite successful, since once on the shelves of pharmacies you can buy Cialis. It should be noted that ICOS undertook the development and testing of the new drug globally, as it was tested before 2002.

That year the representatives of the company made a presentation at the American Urological Association, where they told everyone about the unique properties of this drug – the duration of the action is 36 hours; the time taken out of the body is 17.5 hours, minimal side effects and contraindications. The Cialis birthday can be considered on 6/10/2011, when Tadalafil was approved by the FDA as a drug intended for the treatment of benign hyperplasia and erectile dysfunction.

 

What is Cialis and is It Effective?

It is enough just to talk about the drugs with which the erectile dysfunction is treated, and Viagra comes to mind. The popularity of this medication is due, first of all, to a high-profile advertising campaign (not for nothing advertising the world’s largest advertising agencies). But few know about such a feature that the effectiveness of this all-known drug is 75-85%.

To date, there is a strange tendency – if not helped by Viagra, the man despairs, begins to visit folk healers or use strange means. Although the solution of the problem on the surface, more precisely, on the same shelf in the pharmacy as Viagra is Cialis, a new generation drug whose effectiveness is not only described in colorful advertising brochures, but is proved by clinical trials and by men who use it all over the world. If we talk about the fundamental difference between Viagra, Levitra and Cialis, it is minimal, since all these drugs belong to the same pharmacological group.

 

Tadalafil – the Core of Cialis

The use of Tadalafil allows you to stabilize an erection, and this is already a serious application in order for a man to have a full sexual intercourse. An interesting fact – the effect of taking this remedy becomes noticeable literally in 15-20 minutes after taking (all depends on the degree of excitement and individual characteristics of the organism).

If we talk about PDE5, then this enzyme is contained in the body of any man, as it is formed in the kidneys, lungs, smooth muscles of blood vessels and, naturally, in the genitourinary system. The use of Tadalafil and preparations on its basis allows further stimulating this enzyme. If we talk about the effectiveness of taking medications on the basis of this substance, then it is at the level of 80-85%, and this is a very good result, compared to which not every medicine can.

 

Physico-chemical Features of Cialis

As practice shows, most men before taking Tadalafil ask the question – what is the difference between Cialis and Viagra. Long-term clinical trials have shown that Tadalafil significantly more quickly enters the blood of a man than Sildenafil, so the effect of the drug is noticeable after only 15 minutes.

Despite the fact that doctors recommend taking Cialis an hour before sexual intercourse, men in our country take it literally in a few minutes (then, however, they complain that the drug does not help, but they are to blame – it was necessary to read the instruction). The peculiarity of this drug, which distinguishes it from other drugs for the treatment of erectile dysfunction, is the duration of the action. It is 36 hours!